Alpha-1 Antitrypsin Therapy
Augmentation Therapy for AATD
Alpha-1 Antitrypsin Augmentation Therapy is a specialized treatment for individuals with Alpha-1 Antitrypsin Deficiency, a genetic condition that can lead to serious lung and liver disease. This therapy replaces the missing AAT protein to help protect the lungs.
What is Alpha-1 Deficiency?
Alpha-1 Antitrypsin Deficiency (AATD) is an inherited condition where the liver produces insufficient alpha-1 antitrypsin, a protein that protects the lungs from damage during inflammation.
- Genetic condition affecting lungs
- Can cause early-onset emphysema
- May also affect the liver
How Augmentation Works
Weekly infusions of purified AAT protein travel through the bloodstream to the lungs, where they protect tissue from damage caused by neutrophil elastase, an enzyme that can break down lung tissue.
- Weekly IV infusions
- Protects lung tissue
- Slows disease progression
Symptoms of Alpha-1 Deficiency
Many people with AATD are undiagnosed. If you experience these symptoms, talk to your doctor about testing.
Shortness of Breath
Difficulty breathing, especially with physical activity, is often the first symptom noticed by patients.
Wheezing & Chronic Cough
Persistent respiratory symptoms that may be mistaken for asthma or chronic bronchitis.
Recurrent Respiratory Infections
Frequent lung infections due to reduced lung function and impaired immune protection.
Early-Onset Emphysema
Development of emphysema before age 45, particularly in non-smokers, is a key indicator of AATD.
Alpha-1 Medications We Administer
Our nurses are experienced with all FDA-approved AAT therapies
Prolastin-C
Alpha1-proteinase inhibitor
Zemaira
Alpha1-proteinase inhibitor
Aralast NP
Alpha1-proteinase inhibitor
Glassia
Alpha1-proteinase inhibitor
Benefits of Home Alpha-1 Therapy
Since augmentation therapy requires weekly lifelong infusions, home treatment helps you maintain your normal life.
Comfort of Home
Receive treatment in your familiar environment
Flexible Scheduling
Infusions scheduled around your life
One-on-One Care
Dedicated nurse throughout your infusion
Reduced Infection Risk
Avoid exposure to clinical settings